Metastatic Disease to the Musculoskeletal System   

By John Heiner, M.D., Timothy Kinsella, M.D., and Thomas Zdeblick, M.D. Metastatic Disease to the Musculoskeletal System is a comprehensive text designed for use by clinicians from multiple disciplines. As approximately 70% of people who die of cancer have metastatic musculoskeletal system, it has become a common problem seen by oncologists, orthopedic surgeons, radiation therapists and internists. However, to date, no text has been available that has provided a solid multidisciplinary approach to these conditions. This book has contributors from many disciplines who offer their insight and experience in treating these devastating and complicated problems. TABLE OF CONTENTS: I. INTRODUCTION Incidence and Effect on Society Molecular Mechanisms of Metastatic Disease Pathology of Metastatic Disease II. CLINICAL PRESENTATION Symptoms and Serologic Findings Conventional Techniques in Radiologic Evaluation Role of Bone Scanning and PET Scanning Computer Tomography and Magnetic Resonance Imaging in Radiologic Evaluation Interventional Radiology: Biopsy and Embolization III. NONOPERATIVE TREATMENT Therapy Affecting Bone Resorption and Deposition Radiation Therapy Pharmacologic Management of Bone Cancer Pain Terminal Care and Psychological Consequences of Chronic Bone Cancer Pain IV. MANAGEMENT OF SPECIFIC TUMORS METASTATIC TO BONE Breast Cancer Endocrine Cancer Gastrointestinal Cancer Gynecologic Cancer Hematologic Cancer Lung Cancer Malignant Melanoma and Other Skin Lesions Neural Tumors Prostate Cancer Metastatic Sarcomas Urinary Tract Cancer V. METASTATIC DISEASE TO THE AXIAL SKELETON AND PELVIS Metastatic Disease of the Jaw and Skull Classification of Spinal Metastases Nonoperative vs. Operative Treatment of the Spine Metastatic Disease of the Cervical Spine Metastatic Disease of the Thoracic Spine and Ribs Metastatic Disease of the Lumbar Spine and Sacrum Metastatic Disease of the Pelvis and Acetabulum VI. METASTATIC DISEASE TO THE EXTREMITIES Nonoperative vs. Operative Treatment of Extremity Metastatic Disease Biomechanics of Extremity Fixation in Metastatic Disease Metastatic Disease of the Femoral Neck and Shaft Metastatic Disease of the Distal Femur Metastatic Disease of Tibia and Foot Metastatic Disease of the Humerus and Shoulder Girdle Metastatic Disease of the Distal Humerus, Elbow, Forearm, and Hand Soft Tissue Metastases VII. COMPLICATIONS OF TREATMENT The Effect of Radiation on Tissue and Wound Healing Reconstructions in Delayed Wound Healing Paraneoplastic Syndromes Failure of Fixation in Metastatic Disease to the Pelvis and Extremities 2002. 595 pages, 250 illustrations